Adenosine modulation of neurotransmission in penile erection.
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چکیده
منابع مشابه
Adenosine modulation of neurotransmission in penile erection.
1. Adenosine inhibited the noradrenaline-induced contraction of rabbit corpus cavernosum in a dose-dependent manner. The effect of adenosine was greater in intact corpus cavernosa than in endothelium-denuded preparations. This finding indicates that the relaxing effect of adenosine is partially endothelium-dependent and involved in the release of endothelium-derived relaxing factors. 2. Adenosi...
متن کاملPenile Erection
Hemodynamic Aspects Penile erection and detumescence are primari ly controlled by hemodynamic events. Increased arterial inflow appears to be of primary importance; the contribution of increased venous resistance to the production of penile erection remains controversial. Furthermore, our understanding of precise anatomic details ( including “shunts”) and the neural control of vascular events i...
متن کاملPharmacology of penile erection.
Erection is basically a spinal reflex that can be initiated by recruitment of penile afferents, but also by visual, olfactory, and imaginary stimuli. The reflex involves both autonomic and somatic efferents and is modulated by supraspinal influences. Several central transmitters involved in the erectile control have been identified. Dopamine, acetylcholine, nitric oxide (NO), and peptides, such...
متن کاملIntraoperative penile erection.
OBJECTIVE Penile erection following epidural anesthesia is an infrequent occurrence of unclear etioogy. It is very troublesome to perform the procedure during penile erection and attempting it leads to various complications. Three such cases are reported herein. The literature on the pathophysiology and management of intraoperative penile erection is discussed. METHODS Eighteen hundred patien...
متن کاملAdenosine modulation of neurotransmission in human uterine arteries.
The relaxing effects of adenosine, N-[(R)-1-methyl-2 phenylethyl]-adenosine (R-PIA) and 5-N-ethylcarboxamide adenosine (NECA) were investigated in human uterine arteries precontracted by phenylephrine in vitro. Adenosine, R-PIA and NECA relaxed isolated uterine arteries with intact endothelium, the potency order was NECA > R-PIA > adenosine. When tested on vessels devoid of their endothelium, t...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1994
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1994.tb04366.x